小猪视频app

Form: 4

Statement of changes in beneficial ownership of securities

December 17, 2012

FORM 4
Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).
UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549

STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP OF SECURITIES

Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940
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(Print or Type Responses)
1. Name and Address of Reporting Person *
PFENNIGER RICHARD C JR
 听 2. Issuer Name and Ticker or Trading Symbol
Opko Health, Inc. [OPK] 		5. Relationship of Reporting Person(s) to Issuer
(Check all applicable)
__X__ Director _____ 10% Owner
_____ Officer (give title below) _____ Other (specify below)
(Last)
(First)
(Middle)
小猪视频app HEALTH, INC.,听4400 BISCAYNE BLVD.		 3. Date of Earliest Transaction (Month/Day/Year)
12/14/2012
(Street)

MIAMI,听FL听33137		 4. If Amendment, Date Original Filed(Month/Day/Year)
 6. Individual or Joint/Group Filing(Check Applicable Line)
_X_ Form filed by One Reporting Person
___ Form filed by More than One Reporting Person
(City)
(State)
(Zip)
Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1.Title of Security
(Instr. 3)		 2. Transaction Date (Month/Day/Year) 2A. Deemed Execution Date, if any (Month/Day/Year) 3. Transaction Code
(Instr. 8)		 4. Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4 and 5)		 5. Amount of Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 3 and 4)		 6. Ownership Form: Direct (D) or Indirect (I)
(Instr. 4)		 7. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V Amount (A) or (D) Price
Common Stock 12/14/2012 听 M 听 40,000 A $ 2.78 90,000 D 听
Common Stock 12/14/2012 听 M 听 20,000 A $ 1.78 110,000 D 听
Common Stock 12/14/2012 听 M 听 20,000 A $ 1.54 130,000 D 听
Common Stock 12/14/2012 听 M 听 20,000 A $ 2.05 150,000 D 听

Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
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Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned
(e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security
(Instr. 3)		 2. Conversion or Exercise Price of Derivative Security 3. Transaction Date (Month/Day/Year) 3A. Deemed Execution Date, if any (Month/Day/Year) 4. Transaction Code
(Instr. 8)		 5. Number of Derivative Securities Acquired (A) or Disposed of (D)
(Instr. 3, 4, and 5)		 6. Date Exercisable and Expiration Date
(Month/Day/Year)		 7. Title and Amount of Underlying Securities
(Instr. 3 and 4)		 8. Price of Derivative Security
(Instr. 5)		 9. Number of Derivative Securities Beneficially Owned Following Reported Transaction(s)
(Instr. 4)		 10. Ownership Form of Derivative Security: Direct (D) or Indirect (I)
(Instr. 4)		 11. Nature of Indirect Beneficial Ownership
(Instr. 4)
Code V (A) (D) Date Exercisable Expiration Date Title Amount or Number of Shares
Stock Option (Right to Buy) $ 2.78 12/14/2012 听 M 听 听 40,000 01/24/2009 01/23/2015 Common Stock 40,000 $ 0 0 D 听
Stock Option (Right to Buy) $ 1.78 12/14/2012 听 M 听 听 20,000 08/01/2009 07/30/2015 Common Stock 20,000 $ 0 0 D 听
Stock Option (Right to Buy) $ 1.54 12/14/2012 听 M 听 听 20,000 06/10/2010 06/09/2016 Common Stock 20,000 $ 0 0 D 听
Stock Option (Right to Buy) $ 2.05 12/14/2012 听 M 听 听 20,000 05/27/2011 05/26/2017 Common Stock 20,000 $ 0 0 D 听

Reporting Owners

Reporting Owner Name / Address Relationships
听Director 听10% Owner 听Officer 听Other
PFENNIGER RICHARD C JR
小猪视频app HEALTH, INC.
4400 BISCAYNE BLVD.
MIAMI,听FL听33137		 听 X 听 听 听

Signatures

听Adam Logal, Attorney-in-Fact 听 12/17/2012
**Signature of Reporting Person Date

Explanation of Responses:

* If the form is filed by more than one reporting person, see Instruction 4(b)(v).
** Intentional misstatements or omissions of facts constitute Federal Criminal Violations. See 18 U.S.C. 1001 and 15 U.S.C. 78ff(a).

Note: File three copies of this Form, one of which must be manually signed. If space is insufficient, see Instruction 6 for procedure.

Potential persons who are to respond to the collection of information contained in this form are not required to respond unless the form displays a currently valid OMB number.