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JOINT FILER INFORMATION

NAME:聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽Frost Gamma Investments Trust
ADDRESS:聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽4400 Biscayne Blvd
聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽  Miami, FL 33137

Designated Filer:聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽Phillip Frost, M.D.

Issuer and Ticker Symbol: 聽聽聽聽聽聽聽聽Opko Health, Inc. (OPK)

Date of Event Requiring
Statement:聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽October 3, 2007

FROST GAMMA INVESTMENTS TRUST
聽聽聽聽聽聽聽聽by:聽聽聽聽聽聽/s/ Phillip Frost MD
聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽聽  Phillip Frost, M.D., Trustee