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			JOINT FILER INFORMATION




NAME: 			     Frost Gamma Investments Trust

ADDRESS:			     4400 Biscayne Blvd
				     Miami, FL 33137

Designated Filer:		     Phillip Frost, M.D.

Issuer and Ticker Symbol:    Opko Health, Inc. (OPK)

Date of Event Requiring
Statement:			     October 11, 2007







FROST GAMMA INVESTMENTS TRUST

	by:      /s/ Phillip Frost MD
	         Phillip Frost, M.D., Trustee