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			JOINT FILER INFORMATION




NAME: 			Frost Gamma Investments Trust

ADDRESS:			4400 Biscayne Blvd
				Miami, FL 33137

Designated Filer:		Phillip Frost, M.D.

Issuer and Ticker Symbol: 	Opko Health, Inc. (OPK)

Date of Event Requiring
Statement:			October 18, 2007







FROST GAMMA INVESTMENTS TRUST

	by:     /s/ Phillip Frost, M.D., Trustee
		Phillip Frost, M.D., Trustee